Description

4-Chloro-2-Methylamino-5-Methylthio-6-Piperazinopyrimidine is a high-purity, functionalized pyrimidine derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic cores.
• Agrochemical Synthesis: Serves as a precursor in the design and production of new-generation herbicides, fungicides, or insecticides with specific modes of action.
• Chemical Biology Research: Used as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the scalable production of client-specified target molecules.
• Academic Research: Utilized in university and institutional laboratories for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-Chloro-2-Methylamino-5-Methylthio-6-Piperazinopyrimidine
CAS No.	55921-71-6
Molecular Formula	C10H15ClN6S
Molecular Weight	286.78 g/mol
Synonyms	4-Chloro-2-(methylamino)-5-(methylthio)-6-(piperazin-1-yl)pyrimidine; 6-Piperazino-4-chloro-2-methylamino-5-methylthiopyrimidine; 4-Chloro-6-piperazino-2-methylamino-5-methylthiopyrimidine; 2-Methylamino-4-chloro-5-methylthio-6-piperazinopyrimidine; 5-Methylthio-4-chloro-2-methylamino-6-piperazinopyrimidine; CAS 55921-71-6
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Methylamino-5-Methylthio-6-Piperazinopyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.