Description

4-Chloro-2-(2-Hydroxyethylamino)-6-(4-Methylpiperazino)-5-(Methylthio)Pyrimidine is a sophisticated pyrimidine derivative, a key heterocyclic building block prized for its functional versatility in advanced organic synthesis. This compound matters for its role as a crucial intermediate in the development of active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-purity intermediate to drive innovation in drug discovery and process development.

Application

• Primary intermediate in the synthesis of novel pharmaceutical compounds, especially kinase inhibitors and other targeted therapies.
• Key building block for agrochemical research, used in developing new fungicides or herbicides with specific modes of action.
• Versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Precursor for the synthesis of complex heterocyclic compounds used in material science and specialty chemicals.
• Research chemical in academic and industrial laboratories exploring new chemical entities and reaction pathways.

Basic Information

Product Name	4-Chloro-2-(2-Hydroxyethylamino)-6-(4-Methylpiperazino)-5-(Methylthio)Pyrimidine
CAS No.	55921-70-5
Molecular Formula	C12H21ClN6OS
Molecular Weight	332.85 g/mol
Synonyms	4-Chloro-2-[(2-hydroxyethyl)amino]-6-(4-methyl-1-piperazinyl)-5-(methylthio)pyrimidine; 2-Amino-4-chloro-6-(4-methylpiperazin-1-yl)-5-(methylsulfanyl)pyrimidine derivative; 5-(Methylthio)-4-chloro-2-(2-hydroxyethylamino)-6-(4-methylpiperazino)pyrimidine; 55921-70-5; 4-Chloro-2-(2-hydroxyethylamino)-6-(4-methylpiperazino)-5-methylthiopyrimidine; Pyrimidine, 4-chloro-2-[(2-hydroxyethyl)amino]-6-(4-methyl-1-piperazinyl)-5-(methylthio)-; 6-(4-Methylpiperazin-1-yl)-4-chloro-2-[(2-hydroxyethyl)amino]-5-(methylsulfanyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(2-Hydroxyethylamino)-6-(4-Methylpiperazino)-5-(Methylthio)Pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by advanced analytical techniques like HPLC and NMR. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.