Description

4-Chloro-6-(4-Methylpiperazino)-5-(Methylthio)Pyrimidin-2-Amine is a high-value pyrimidine derivative, a key heterocyclic building block in advanced organic synthesis. Its molecular structure, featuring chloro, methylpiperazino, and methylthio substituents, makes it a versatile intermediate for constructing complex molecules with targeted biological activity. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the discovery and synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly in therapeutic areas requiring complex heterocyclic cores.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where the pyrimidine scaffold is a common bioactive motif.
• Chemical Biology Probe Synthesis: Employed to create molecular tools for studying biological pathways and target validation in drug discovery.
• Material Science Research: Acts as a building block for specialty polymers or organic electronic materials that incorporate nitrogen-containing heterocycles.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic & Industrial R&D: Used in research laboratories for methodological development and exploring new chemical reactions.

Basic Information

Product Name	4-Chloro-6-(4-Methylpiperazino)-5-(Methylthio)Pyrimidin-2-Amine
CAS No.	55921-66-9
Molecular Formula	C10H15ClN6S
Molecular Weight	286.78 g/mol
Synonyms	2-Amino-4-chloro-6-(4-methyl-1-piperazinyl)-5-(methylthio)pyrimidine; 4-Chloro-6-(4-methylpiperazin-1-yl)-5-(methylsulfanyl)pyrimidin-2-amine; 5-(Methylthio)-4-chloro-6-(4-methyl-1-piperazinyl)-2-pyrimidinamine; 55921-66-9; 4-Chloro-6-(4-methylpiperazino)-5-methylthiopyrimidin-2-amine
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-(4-Methylpiperazino)-5-(Methylthio)Pyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.