Description

(4-(1,1-Difluoroethyl)Phenyl)Methanol CAS NO 55805-25-9 is a specialized fluorinated aromatic alcohol, serving as a high-value building block in advanced organic synthesis. Its unique structure, featuring a difluoroethyl group, makes it a critical intermediate for introducing fluorine atoms into target molecules, thereby enhancing their metabolic stability, lipophilicity, and binding affinity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing next-generation active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and antiviral research where fluorination is a common strategy.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the difluoroethyl moiety can improve biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs) due to its ability to modify dielectric anisotropy and viscosity.
• Polymer Science: Employed as a monomer or modifier in creating specialty polymers with enhanced chemical resistance, thermal stability, and surface properties.
• Organic Electronics: Acts as a building block for materials used in organic light-emitting diodes (OLEDs) and semiconductors, where fluorine substitution tunes electronic properties.
• Chemical Research & Development: A versatile reagent in medicinal chemistry and material science labs for structure-activity relationship (SAR) studies and novel compound library generation.

Basic Information

Product Name	(4-(1,1-Difluoroethyl)Phenyl)Methanol
CAS No.	55805-25-9
Molecular Formula	C9H10F2O
Molecular Weight	172.17 g/mol
Synonyms	4-(1,1-Difluoroethyl)benzyl alcohol; [4-(1,1-Difluoroethyl)phenyl]methanol; 1-[4-(Hydroxymethyl)phenyl]-1,1-difluoroethane; α,α-Difluoro-4-methylbenzyl alcohol (derivative); Benzenemethanol, 4-(1,1-difluoroethyl)-; p-(1,1-Difluoroethyl)benzyl alcohol
EINECS	Contact for details

Quality Control

Our (4-(1,1-Difluoroethyl)Phenyl)Methanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications in cGMP environments and rigorous R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is sensitive to strong bases and fluorides; keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.