Description

4'-Hydroxyphenprocoumon is a key synthetic intermediate and reference standard in the pharmaceutical and fine chemical industries. This compound is of significant importance for research and development in anticoagulant pharmacology and metabolic studies. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in drug discovery and analytical method development. The product is supplied with a focus on high purity and batch-to-batch consistency to meet stringent research and production requirements.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis and research of anticoagulant agents and related pharmaceutical compounds.
• Reference Standard: Used as a certified reference material (CRM) for quality control, analytical method validation, and regulatory compliance in pharmaceutical analysis.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research for studying the biotransformation of phenprocoumon and related drugs.
• Biochemical Research: Serves as a tool compound in enzymatic assays and studies targeting vitamin K epoxide reductase and other relevant biological targets.
• Academic & Industrial R&D: Fundamental material for novel drug discovery projects and chemical synthesis research within university and corporate laboratories.

Basic Information

Product Name	4'-Hydroxyphenprocoumon
CAS No.	55789-09-8
Molecular Formula	C₁₈H₁₆O₅
Molecular Weight	312.32 g/mol
Synonyms	4'-Hydroxy-3-(1-phenylpropyl)-4-hydroxycoumarin; 4-Hydroxyphenprocoumon; Phenprocoumon 4'-Hydroxy Metabolite; 3-(1-Phenylpropyl)-4-hydroxy-2H-1-benzopyran-2-one-4'-ol; Marcumar Metabolite
EINECS	Contact for details

Quality Control

Our 4'-Hydroxyphenprocoumon is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for that lot. We adhere to relevant industry guidelines to support our customers' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.