Description

Bombesin (8-14) CAS NO 55749-98-9 is a bioactive peptide fragment derived from the full-length bombesin peptide, known for its high binding affinity to gastrin-releasing peptide (GRP) receptors. This specific sequence is critical for research into neuropeptide signaling pathways and receptor-ligand interactions. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on oncology, metabolic disorders, and neurological research.

Application

• Biomedical Research: Used as a key reagent in studying the role of bombesin-like peptides in cell proliferation, tumor growth, and cancer biology.
• Receptor Binding Assays: Essential for in vitro competitive binding studies to characterize and quantify GRP receptor expression and affinity.
• Drug Discovery & Development: Serves as a reference standard and pharmacophore model for developing novel therapeutic agents targeting GRP receptors.
• Neuroscience Studies: Applied in research investigating neuromodulation, satiety signaling, and stress responses within the central nervous system.
• Diagnostic Tool Development: Potential use in the development of imaging probes and diagnostic kits for cancers that overexpress bombesin receptors.

Basic Information

Product Name	Bombesin (8-14)
CAS No.	55749-98-9
Molecular Formula	C38H59N13O10S
Molecular Weight	889.99 g/mol
Synonyms	Bombesin (8-14) fragment; Pyr-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2; Pyr-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-amide; GRP (18-27); Neuromedin C (8-14); [Tyr4]Bombesin (8-14) (related analog); Gastrin-Releasing Peptide fragment; BN (8-14)
EINECS	Contact for details

Quality Control

Our Bombesin (8-14) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets exacting research-grade specifications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.