Description

1-(5-Hydroxy-2-Pyrimidinyl)Piperazine is a high-purity heterocyclic building block and pharmaceutical intermediate of significant commercial interest. Its core value lies in its versatile piperazine-pyrimidine scaffold, which is a privileged structure in medicinal chemistry for designing bioactive molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Chemical Synthesis: Serves as a versatile precursor for creating more complex piperazine and pyrimidine derivatives in organic chemistry.
• Biochemical Research: Utilized as a ligand or molecular scaffold in biochemical assays and for studying enzyme interactions.
• Material Science: Potential monomer or additive in the synthesis of specialized polymers and advanced materials.

Basic Information

Product Name	1-(5-Hydroxy-2-Pyrimidinyl)Piperazine
CAS No.	55745-85-2
Molecular Formula	C8H12N4O
Molecular Weight	180.21 g/mol
Synonyms	5-Hydroxy-2-(piperazin-1-yl)pyrimidine; 1-(5-Hydroxypyrimidin-2-yl)piperazine; 2-(1-Piperazinyl)-5-pyrimidinol; Piperazine, 1-(5-hydroxy-2-pyrimidinyl)-; 5-Hydroxy-2-piperazin-1-ylpyrimidine
EINECS	Contact for details

Quality Control

Our 1-(5-Hydroxy-2-Pyrimidinyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting purity, assay, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.