Description

2-(Piperazin-1-Yl)Pyrimidin-4(3H)-One is a high-purity heterocyclic organic compound, serving as a critical pharmaceutical intermediate and versatile building block in medicinal chemistry. Its value lies in its piperazine-pyrimidinone core, a privileged scaffold for designing bioactive molecules with targeted therapeutic effects. This compound is essential for research and development laboratories in the pharmaceutical, agrochemical, and fine chemical industries seeking to synthesize novel compounds for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and combinatorial chemistry to develop new molecular entities with optimized biological activity.
• Agrochemical Development: Serves as a precursor in the creation of novel herbicides, fungicides, or plant growth regulators.
• Chemical Biology Probes: Utilized in the development of tool compounds and probes for studying biological pathways and target validation.
• Fine Chemical Synthesis: Acts as a versatile synthon for constructing complex heterocyclic systems in custom synthesis and contract manufacturing.

Basic Information

Product Name	2-(Piperazin-1-Yl)Pyrimidin-4(3H)-One
CAS No.	55745-84-1
Molecular Formula	C8H12N4O
Molecular Weight	180.21 g/mol
Synonyms	4(3H)-Pyrimidinone, 2-(1-piperazinyl)-; 2-Piperazin-1-yl-3H-pyrimidin-4-one; 2-(Piperazin-1-yl)pyrimidin-4-ol; 2-(1-Piperazinyl)-4(3H)-pyrimidinone; 4-Hydroxy-2-(piperazin-1-yl)pyrimidine; 2-Piperazinyl-4-pyrimidinol; 55745-84-1; 2-Piperazin-1-yl-1H-pyrimidin-4-one
EINECS	Contact for details

Quality Control

Our 2-(Piperazin-1-Yl)Pyrimidin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.