Description

4-[(2,4-Diaminopyrimidin-5-Yl)Methyl]-2,6-Dimethoxy-Benzamide is a high-purity, specialized organic compound featuring a benzamide core linked to a diaminopyrimidine moiety. This unique molecular architecture makes it a valuable pharmaceutical intermediate and research chemical for the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis sectors seeking to create targeted bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of dihydrofolate reductase (DHFR) inhibitors and other enzyme-targeting drugs.
• Antimicrobial Agent Research: Serves as a precursor for developing novel antibacterial and antifungal compounds due to its pyrimidine structure.
• Oncology Research: Used in the discovery and development of targeted cancer therapies, particularly those interfering with folate metabolism.
• Chemical Biology Probe: Employed in biochemical research to study enzyme function and cellular pathways.
• Fine Chemical Synthesis: A versatile intermediate for constructing complex heterocyclic compounds in custom synthesis projects.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	4-[(2,4-Diaminopyrimidin-5-Yl)Methyl]-2,6-Dimethoxy-Benzamide
CAS No.	55687-57-5
Molecular Formula	C14H17N5O3
Molecular Weight	303.32 g/mol
Synonyms	2,6-Dimethoxy-4-[(2,4-diamino-5-pyrimidinyl)methyl]benzamide; 5-[(3-Carbamoyl-2,4-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine; 4-[(2,4-Diamino-5-pyrimidinyl)methyl]-2,6-dimethoxybenzamide; Benzamide, 4-[(2,4-diamino-5-pyrimidinyl)methyl]-2,6-dimethoxy-; 55687-57-5; 2,4-Diamino-5-(3-carbamoyl-2,4-dimethoxybenzyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 4-[(2,4-Diaminopyrimidin-5-Yl)Methyl]-2,6-Dimethoxy-Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.