Description

2-Fluorobenzene-1,4-Diol is a fluorinated dihydroxybenzene derivative, a versatile organic building block prized for its unique electronic and steric properties imparted by the fluorine substituent. This compound is critical for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where precise molecular modification is required. It serves as a key intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom improves bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core structure in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials for electronic displays.
• Polymer Modification: Acts as a monomer or modifier to introduce fluorine into polymer backbones, enhancing chemical resistance and thermal stability.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create complex, fluorinated aromatic systems for research and development.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized fluorinated dyes and pigments with unique color fastness and spectral properties.

Basic Information

Product Name	2-Fluorobenzene-1,4-Diol
CAS No.	55660-73-6
Molecular Formula	C6H5FO2
Molecular Weight	128.10 g/mol
Synonyms	2-Fluoro-1,4-benzenediol; 2-Fluorohydroquinone; 1,4-Dihydroxy-2-fluorobenzene; 2-Fluoroquinol; Fluorohydroquinone; 2-Fluorobenzene-1,4-diol; 2-F-DHQ; 2-Fluorodihydroxybenzene
EINECS	Contact for details

Quality Control

Our 2-Fluorobenzene-1,4-Diol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.