Description

4-o-[(2S)-3α-(Acetylamino)-6-(Aminomethyl)-3,4-Dihydro-2H-Pyran-2α-Yl]-6-o-[3-Deoxy-4-C-Methyl-3-(Methylamino)-β-L-Arabinopyranosyl]-2-Deoxy-D-Streptamine is a structurally complex aminoglycoside derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel antibiotics and other bioactive molecules. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing next-generation therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthetic pathways for novel aminoglycoside antibiotics and related therapeutic compounds.
• Research & Development: Used as a high-purity reference standard in analytical method development, pharmacokinetic studies, and metabolic research.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies targeting bacterial ribosomes and other biological pathways.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of specialized active pharmaceutical ingredients (APIs).
• Quality Control: Essential as a certified reference material (CRM) for the identity and purity testing of related drug substances in QC laboratories.

Basic Information

Item	Detail
Product Name	4-o-[(2S)-3α-(Acetylamino)-6-(Aminomethyl)-3,4-Dihydro-2H-Pyran-2α-Yl]-6-o-[3-Deoxy-4-C-Methyl-3-(Methylamino)-β-L-Arabinopyranosyl]-2-Deoxy-D-Streptamine
CAS No.	55649-82-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2-Deoxy-4-O-[3α-(acetylamino)-6-(aminomethyl)-3,4-dihydro-2H-pyran-2α-yl]-6-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl]-D-streptamine; 4-O-[(2S)-3α-(Acetylamino)-6-(aminomethyl)-3,4-dihydro-2H-pyran-2α-yl]-6-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl]-2-deoxy-D-streptamine; Antibiotic G-418 intermediate; Geneticin related compound; Aminoglycoside derivative 55649-82-6.
EINECS	Contact for details

Quality Control

Our 4-o-[(2S)-3α-(Acetylamino)-6-(Aminomethyl)-3,4-Dihydro-2H-Pyran-2α-Yl]-6-o-[3-Deoxy-4-C-Methyl-3-(Methylamino)-β-L-Arabinopyranosyl]-2-Deoxy-D-Streptamine is produced and tested under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.