Description

6-Methyl-N,n-Bis(Trimethylsilyl)-4-[(Trimethylsilyl)Oxy]-2-Pteridinamine is a highly functionalized pteridine derivative featuring multiple trimethylsilyl (TMS) protecting groups. This compound is a crucial advanced pharmaceutical intermediate and a versatile building block in organic synthesis, valued for its role in constructing complex heterocyclic systems. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel pteridine-based drug candidates, including potential kinase inhibitors and antifolate agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the pteridine scaffold.
• Organic Synthesis Reagent: Serves as a protected precursor for introducing the 2-amino-4-hydroxy-6-methylpteridine moiety into more complex molecules under mild conditions.
• Material Science Research: Potential precursor for nitrogen-rich heterocyclic compounds with applications in specialty materials and ligands for catalysis.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	6-Methyl-N,n-Bis(Trimethylsilyl)-4-[(Trimethylsilyl)Oxy]-2-Pteridinamine
CAS No.	55649-43-9
Molecular Formula	C17H35N5OSi3
Molecular Weight	425.75 g/mol
Synonyms	2-Pteridinamine, 6-methyl-N,N-bis(trimethylsilyl)-4-[(trimethylsilyl)oxy]-; 6-Methyl-4-(trimethylsiloxy)-N,N-bis(trimethylsilyl)-2-pteridinamine; 4-(Trimethylsiloxy)-6-methyl-N,N-bis(trimethylsilyl)-2-pteridinamine; Tris(trimethylsilyl) Derivative of 2-Amino-4-hydroxy-6-methylpteridine; TMS-protected 2-Amino-4-hydroxy-6-methylpteridine; 2-Amino-4-hydroxy-6-methylpteridine tris(trimethylsilyl) ether; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 6-Methyl-N,n-Bis(Trimethylsilyl)-4-[(Trimethylsilyl)Oxy]-2-Pteridinamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development projects with custom synthesis and purity grades upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can compromise product integrity. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Standard Grade)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.