Description

2(1H)-Pyrimidinone, 4-Amino-1-[(2S)-2,3-Dihydroxypropyl]- is a high-purity, chiral pyrimidinone derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and building block for the development of novel active ingredients. It is primarily required by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the synthesis of nucleoside analogs and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a precursor in the study of enzyme inhibitors and the development of novel biochemical probes.
• Organic Synthesis: Serves as a versatile building block for constructing complex heterocyclic compounds with potential biological activity.
• Active Pharmaceutical Ingredient (API) Development: Employed in the synthetic pathways for developing new drug candidates targeting various diseases.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial manufacturing of specialty chemicals.

Basic Information

Product Name	2(1H)-Pyrimidinone, 4-Amino-1-[(2S)-2,3-Dihydroxypropyl]-
CAS No.	55559-70-1
Molecular Formula	C7H11N3O3
Molecular Weight	185.18 g/mol
Synonyms	4-Amino-1-[(2S)-2,3-dihydroxypropyl]-1H-pyrimidin-2-one; (S)-4-Amino-1-(2,3-dihydroxypropyl)-1H-pyrimidin-2(1H)-one; 4-Amino-1-(2,3-dihydroxypropyl)pyrimidin-2(1H)-one; 1-(2,3-Dihydroxypropyl)-4-aminopyrimidin-2(1H)-one; 4-Amino-1-(2,3-dihydroxypropyl)-2-pyrimidinone; Acyclic Nucleoside Analogue Intermediate
EINECS	Contact for details

Quality Control

Our production of 2(1H)-Pyrimidinone, 4-Amino-1-[(2S)-2,3-Dihydroxypropyl]- adheres to stringent quality management protocols. The material is manufactured under controlled conditions and undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure high chemical and isomeric purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic; therefore, containers should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.