Description

3-Methoxy-n-[(Pentafluorophenyl)Methylene]-4-[(Trimethylsilyl)Oxy]Benzeneethanamine CAS NO 55556-69-9 is a specialized, high-value organosilicon and fluorinated aromatic compound. This advanced intermediate is critical for synthesizing complex molecules in pharmaceutical and agrochemical research, offering unique reactivity and structural features. It is primarily utilized by R&D chemists and process development scientists in the fine chemical and life science industries to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the pentafluorophenyl group can contribute to lipophilicity and binding affinity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, or advanced coatings with specific surface properties.
• Chemical Biology Probe Synthesis: Employed to create tagged molecules or affinity probes for studying biological pathways and protein interactions, leveraging its distinct chemical handle.
• Organic Synthesis Reagent: Acts as a protected amine and silyl ether synthon in multi-step synthetic routes, enabling complex molecular architectures.

Basic Information

Product Name	3-Methoxy-n-[(Pentafluorophenyl)Methylene]-4-[(Trimethylsilyl)Oxy]Benzeneethanamine
CAS No.	55556-69-9
Molecular Formula	C19H20F5NO2Si
Molecular Weight	417.45 g/mol
Synonyms	4-[(Trimethylsilyl)oxy]-N-[(2,3,4,5,6-pentafluorophenyl)methylene]-3-methoxybenzeneethanamine; N-(Pentafluorobenzylidene)-2-[4-(trimethylsilyloxy)-3-methoxyphenyl]ethanamine; 2-(4-(Trimethylsilyloxy)-3-methoxyphenyl)-N-(2,3,4,5,6-pentafluorobenzylidene)ethanamine; Pentafluorobenzylidene-protected TMS ether of homovanillylamine; PFB-TMS-HVA amine derivative
EINECS	Contact for details

Quality Control

Every batch of 3-Methoxy-n-[(Pentafluorophenyl)Methylene]-4-[(Trimethylsilyl)Oxy]Benzeneethanamine is produced and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.