Description

2-(Dimethylamino)-6-(Trifluoromethyl)-4-Pyrimidinol is a versatile pyrimidine derivative characterized by its dimethylamino and trifluoromethyl substituents, which confer unique chemical reactivity and physical properties. This compound serves as a critical advanced pharmaceutical intermediate and a valuable building block in synthetic organic chemistry. It is primarily required by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and antiviral applications.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides, leveraging the biological activity of the pyrimidine core.
• Organic Synthesis Building Block: Utilized in medicinal and combinatorial chemistry for constructing complex heterocyclic compounds due to its reactive hydroxyl and amino groups.
• Material Science Research: Investigated for use in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D for method development and exploring new reaction pathways involving fluorinated heterocycles.

Basic Information

Product Name	2-(Dimethylamino)-6-(Trifluoromethyl)-4-Pyrimidinol
CAS No.	55545-80-7
Molecular Formula	C7H8F3N3O
Molecular Weight	207.16 g/mol
Synonyms	6-(Trifluoromethyl)-2-(dimethylamino)pyrimidin-4-ol; 2-Dimethylamino-6-trifluoromethyl-4-pyrimidinol; 4-Pyrimidinol, 2-(dimethylamino)-6-(trifluoromethyl)-; 2-(N,N-Dimethylamino)-6-(trifluoromethyl)-4-hydroxypyrimidine; 6-Trifluoromethyl-2-dimethylaminopyrimidin-4-ol; 2-Dimethylamino-6-trifluoromethyl-4(1H)-pyrimidinone; 4-Hydroxy-2-dimethylamino-6-trifluoromethylpyrimidine
EINECS	Contact for details

Quality Control

Our 2-(Dimethylamino)-6-(Trifluoromethyl)-4-Pyrimidinol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.