Description

Motilin, Nle(13)- is a synthetic analog of the gastrointestinal peptide hormone motilin, designed for enhanced stability and research utility. This compound is critical for studying gastrointestinal motility, hormone-receptor interactions, and potential therapeutic pathways. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in metabolic and digestive system research.

Application

• Gastrointestinal Motility Research: Used as a key pharmacological tool to study the regulation of gastric and intestinal contractions.
• Receptor Binding Studies: Employed in assays to investigate the binding affinity and activation mechanisms of the motilin receptor (MLNR).
• Drug Discovery & Development: Serves as a reference standard and lead compound in the development of prokinetic agents for motility disorders.
• Biochemical & Physiological Studies: Applied in vitro and in vivo to understand the role of motilin in interdigestive migrating motor complexes (MMC).
• Academic & Pharmaceutical R&D: Essential for basic research and preclinical studies focused on digestive health and endocrine signaling.

Basic Information

Product Name	Motilin, Nle(13)-
CAS No.	55524-56-6
Molecular Formula	C147H238N42O43S2
Molecular Weight	~3299.9 g/mol
Synonyms	Norleucine(13)-Motilin; [Nle13]-Motilin; Motilin (human, porcine) [Nle13]-; Motilin, 13-Norleucine-; 13-Norleucinemotilin; MLN; Gastrointestinal Motility Peptide Analog
EINECS	Contact for details

Quality Control

Our Motilin, Nle(13)- is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. A Certificate of Analysis (COA) detailing purity, peptide content, and solvent residues is provided to ensure compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.