Description

Neurotensin is a tridecapeptide neurotransmitter and neuromodulator that plays a critical role in the central nervous system and gastrointestinal tract. Its primary value lies in its potent biological activity, influencing dopamine pathways, pain modulation, and gut motility. This makes it an essential research chemical for neuroscientists, pharmacologists, and biochemists investigating neurological disorders, psychiatric conditions, and digestive physiology. Neurotensin CAS NO 55508-42-4 is supplied as a high-purity peptide for reliable and reproducible experimental results.

Application

• Neuroscience Research: Used to study its role as a neurotransmitter and its interactions with dopamine systems in models of schizophrenia, Parkinson's disease, and drug addiction.
• Pharmacological Studies: Serves as a reference standard and active agent in the development and screening of novel neurotensin receptor agonists and antagonists.
• Biochemical Assays: Employed in receptor binding studies, cell signaling experiments, and enzyme activity tests to elucidate its mechanism of action.
• Gastrointestinal Research: Investigated for its effects on gut motility, secretion, and its potential role in conditions like irritable bowel syndrome (IBS).
• Pain Research: Utilized in studies exploring its antinociceptive (pain-blocking) properties and central nervous system pathways.
• Cell Culture & In Vitro Models: Applied in tissue culture to examine its effects on cell proliferation, differentiation, and apoptosis.

Basic Information

Product Name	Neurotensin
CAS No.	55508-42-4
Molecular Formula	C₇₈H₁₂₁N₂₁O₂₀
Molecular Weight	1672.9 g/mol
Synonyms	Neurotensin (1-13); L-Pyroglutamyl-L-leucyl-L-tyrosyl-L-glutamyl-L-asparaginyl-L-lysyl-L-prolyl-L-arginyl-L-arginyl-L-prolyl-L-tyrosyl-L-isoleucyl-L-leucine; NT; NT (1-13); pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu; H-pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH
EINECS	Contact for details

Quality Control

Our Neurotensin is manufactured under strict quality management systems to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for peptide synthesis and can provide material traceable to primary reference standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Assay (HPLC)	≥ 95%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Acetate Content (HPIC)	≤ 10%
Solubility	Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.