Description

o-3-Deoxy-3-(Formylamino)-α-D-Glucopyranosyl-(1→6)-o-[2,3,6-Trideoxy-2,6-Bis(Formylamino)-α-D-Ribo-Hexopyranosyl-(1→4)]-2-Deoxy-N,N''-Diformyl-D-Streptamine is a complex, semi-synthetic derivative of streptamine, representing a key intermediate or reference standard in advanced pharmaceutical research. Its intricate glycosidic structure is of significant interest for the development and analysis of novel aminoglycoside antibiotics. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in antimicrobial drug discovery, process chemistry, and analytical method development.

Application

• Pharmaceutical Reference Standard: Serves as a critical high-purity standard for the quality control and analytical testing (HPLC, LC-MS) of complex antibiotic formulations.
• Antibiotic Research & Development: Used as a key synthetic intermediate or a model compound in the research of next-generation aminoglycoside antibiotics to combat resistant bacterial strains.
• Biochemical Studies: Employed in studies investigating the structure-activity relationships (SAR) and molecular mechanisms of aminoglycoside action and resistance.
• Process Chemistry & Scale-up: Acts as a benchmark or intermediate in the optimization of synthetic routes for complex carbohydrate-based active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for glycoscience, medicinal chemistry, and microbiology research projects.

Basic Information

Product Name	o-3-Deoxy-3-(Formylamino)-α-D-Glucopyranosyl-(1→6)-o-[2,3,6-Trideoxy-2,6-Bis(Formylamino)-α-D-Ribo-Hexopyranosyl-(1→4)]-2-Deoxy-N,N''-Diformyl-D-Streptamine
CAS No.	55480-32-5
Molecular Formula	C26H43N5O15
Molecular Weight	665.65 g/mol
Synonyms	D-Streptamine, N,N''-diformyl-O-3-deoxy-3-(formylamino)-α-D-glucopyranosyl-(1→6)-O-[2,3,6-trideoxy-2,6-bis(formylamino)-α-D-ribo-hexopyranosyl-(1→4)]-2-deoxy-; 3'''-N-Formyl-6'''-N-formyl-3-N-formyl-2''-deoxy-2''-N-formylparomomycin; Paromomycin derivative; 3''',6''',3,2''-Tetra-N-formylparomomycin; Formylparomomycin; Aminoglycoside derivative intermediate; Antibiotic research compound
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to stringent quality management systems. Each batch is subjected to comprehensive analytical characterization, including HPLC for purity determination, mass spectrometry (MS) for identity confirmation, and NMR for structural verification. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting the results against agreed specifications to ensure consistency and reliability for your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.