Description

5''-Amino-4',5''-Dideoxybutirosin A is a semi-synthetic derivative of the aminoglycoside antibiotic butirosin, characterized by specific structural modifications that can alter its biological activity and physicochemical properties. This compound is of significant interest in pharmaceutical research and development, particularly for the synthesis of novel antibiotic analogs and as a key intermediate in medicinal chemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for developing new therapeutic agents and studying structure-activity relationships.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel aminoglycoside antibiotic derivatives and analogs.
• Antibiotic Research: Used in microbiological and biochemical research to study mechanisms of action, resistance, and to screen for new antibacterial activities.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the pharmacokinetic and pharmacodynamic profiles of antibiotic candidates.
• Bioconjugation: The amino group provides a handle for conjugation with other molecules, such as fluorescent probes or targeting moieties, for diagnostic or targeted therapy applications.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation in antibiotic analysis.

Basic Information

Product Name	5''-Amino-4',5''-Dideoxybutirosin A
CAS No.	55480-22-3
Molecular Formula	C₂₁H₄₁N₅O₁₀
Molecular Weight	547.58 g/mol
Synonyms	4',5''-Dideoxy-5''-aminobutirosin A; 5''-Amino-4',5''-dideoxybutirosin; Butirosin A, 5''-amino-4',5''-dideoxy-; 4',5''-Dideoxy-5''-aminoneamine; 1-N-[(S)-4-Amino-2-hydroxybutyryl]-5''-amino-4',5''-dideoxykanamycin B
EINECS	Contact for details

Quality Control

Our 5''-Amino-4',5''-Dideoxybutirosin A is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.