Description

4-Chloro-2-(tert-Butylamino)-6-(4-Methylpiperazino)-5-(Methylthio)Pyrimidine is a high-value, multi-functional pyrimidine derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its complex structure, featuring chloro, tert-butylamino, methylpiperazino, and methylthio substituents, makes it a versatile building block for constructing pharmacologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for synthesizing novel heterocyclic compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the presence of the piperazine moiety.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its pyrimidine core for bioactivity.
• Chemical Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and the construction of complex molecular libraries for high-throughput screening.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands in coordination chemistry and catalysis research.
• Academic & Institutional R&D: Utilized in university and contract research organization (CRO) laboratories for fundamental research in heterocyclic chemistry.

Basic Information

Product Name	4-Chloro-2-(tert-Butylamino)-6-(4-Methylpiperazino)-5-(Methylthio)Pyrimidine
CAS No.	55477-20-8
Molecular Formula	C14H25ClN6S
Molecular Weight	344.91 g/mol
Synonyms	4-Chloro-2-[(1,1-dimethylethyl)amino]-6-(4-methyl-1-piperazinyl)-5-(methylthio)pyrimidine; 2-(tert-Butylamino)-4-chloro-6-(4-methylpiperazino)-5-(methylthio)pyrimidine; 5-(Methylthio)-2-(tert-butylamino)-4-chloro-6-(4-methyl-1-piperazinyl)pyrimidine; CAS 55477-20-8; 4-Chloro-2-(tert-butylamino)-6-(4-methylpiperazin-1-yl)-5-(methylsulfanyl)pyrimidine; 4-Chloro-2-(tert-butylamino)-6-(4-methylpiperazin-1-yl)-5-(methylthio)pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(tert-Butylamino)-6-(4-Methylpiperazino)-5-(Methylthio)Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure consistent quality and reliable performance in your synthesis. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.