Description

n-Ethyl-4-Chloro-6-(4-Methylpiperazino)-5-(Methylthio)Pyrimidin-2-Amine is a high-purity, functionalized pyrimidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile chemical building block for the development of novel active ingredients. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential kinase inhibitors, antiviral agents, and other biologically active molecules.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and plant growth regulators.
• Chemical Synthesis: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Academic & Industrial R&D: Employed in research laboratories for exploring new heterocyclic chemistry and reaction pathways.
• Custom Synthesis: Starting material for the contract manufacturing of complex, high-value specialty chemicals.

Basic Information

Product Name	n-Ethyl-4-Chloro-6-(4-Methylpiperazino)-5-(Methylthio)Pyrimidin-2-Amine
CAS No.	55477-17-3
Molecular Formula	C12H20ClN5S
Molecular Weight	301.84 g/mol
Synonyms	4-Chloro-6-(4-methyl-1-piperazinyl)-5-(methylthio)-2-(ethylamino)pyrimidine; 2-Amino-4-chloro-6-(4-methylpiperazino)-5-(methylthio)pyrimidine, N-ethyl-; 4-Chloro-6-(4-methylpiperazinyl)-5-methylsulfanyl-2-ethylaminopyrimidine; 5-(Methylthio)-4-chloro-6-(4-methyl-1-piperazinyl)-2-(ethylamino)pyrimidine; 55477-17-3; Ethyl-[4-chloro-6-(4-methyl-piperazin-1-yl)-5-methylsulfanyl-pyrimidin-2-yl]-amine
EINECS	Contact for details

Quality Control

Our n-Ethyl-4-Chloro-6-(4-Methylpiperazino)-5-(Methylthio)Pyrimidin-2-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.