Description

Nα,1-Bis(Trifluoroacetyl)-L-Tryptophan Butyl Ester is a protected derivative of the essential amino acid L-tryptophan, featuring trifluoroacetyl groups and a butyl ester moiety. This compound is a critical building block in peptide synthesis and pharmaceutical research, offering enhanced stability and solubility for complex chemical transformations. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and advanced biochemical tools.

Application

• Pharmaceutical Intermediate: Serves as a key protected amino acid derivative in the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics.
• Biochemical Research: Used as a specialized reagent in proteomics and metabolic pathway studies, particularly where tryptophan modification is required.
• Fine Chemical Synthesis: Acts as a precursor for the synthesis of more complex molecules, including fluorescent probes and enzyme inhibitors.
• Agrochemical Development: Employed in research for creating novel bioactive compounds with potential applications in crop protection.
• Academic & Industrial R&D: A valuable tool for chemists in universities and corporate R&D labs exploring new synthetic methodologies and drug discovery.

Basic Information

Product Name	Nα,1-Bis(Trifluoroacetyl)-L-Tryptophan Butyl Ester
CAS No.	55282-24-1
Molecular Formula	C21H20F6N2O4
Molecular Weight	478.39 g/mol
Synonyms	Nα,N1-Bis(trifluoroacetyl)-L-tryptophan butyl ester; L-Tryptophan, Nα,N1-bis(trifluoroacetyl)-, butyl ester; Butyl Nα,N1-bis(2,2,2-trifluoroacetyl)-L-tryptophanate; Nα,N1-Di(trifluoroacetyl)-L-tryptophan butyl ester; BTF-L-Trp-OBu; (S)-2-((Bis(trifluoroacetyl)amino)-3-(1H-indol-3-yl)propanoic acid butyl ester; Protected L-Tryptophan butyl ester; TFA-Tryptophan-OBut ester
EINECS	Contact for details

Quality Control

Our Nα,1-Bis(Trifluoroacetyl)-L-Tryptophan Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.