Description

n-Phenylacetyl-L-Homoserine Lactone CAS NO 55154-48-8 is a high-purity synthetic derivative of homoserine lactone, a key structural motif in bacterial quorum sensing signaling molecules. This compound is of significant value as a critical research-grade biochemical and a versatile chemical building block for advanced organic synthesis. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers focused on developing novel bioactive agents and studying microbial communication pathways.

Application

• Quorum Sensing Research: A vital tool for studying and modulating bacterial cell-to-cell communication, biofilm formation, and virulence factor expression.
• Pharmaceutical Intermediates: Serves as a key synthetic precursor for the development of novel anti-infective agents and quorum sensing inhibitors (QSIs).
• Biochemical Reagents: Used in enzymatic assays and as a standard reference material in analytical laboratories for method development and validation.
• Agrochemical Research: Investigated for the development of next-generation, environmentally friendly agents that disrupt pathogenic bacterial signaling in plants.
• Academic & Industrial R&D: Fundamental building block in organic synthesis for creating libraries of N-acyl homoserine lactone (AHL) analogs with diverse biological activities.

Basic Information

Item	Details
Product Name	n-Phenylacetyl-L-Homoserine Lactone
CAS No.	55154-48-8
Molecular Formula	C13H15NO3
Molecular Weight	233.26 g/mol
Synonyms	N-(Phenylacetyl)-L-homoserine lactone; Phenylacetylhomoserine lactone; N-Phenylacetyllactone; L-N-Phenylacetylhomoserine lactone; N-[(3S)-Tetrahydro-2-oxo-3-furanyl]-2-phenylacetamide; AHL analog; Quorum sensing molecule analog; N-Phenylacetyl-L-HSL
EINECS	Contact for details

Quality Control

Our n-Phenylacetyl-L-Homoserine Lactone is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of GMP and ISO standards for laboratory chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.