Description

Glutaryl-Gly-Gly-Phe-β-Na is a synthetic peptide derivative, specifically a glutaryl-tetrapeptide amide, with the CAS registry number 55145-12-5. This compound serves as a crucial intermediate and biochemical research tool for studying protease activity and developing enzyme inhibitors. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on enzymology and peptide-based drug discovery.

Application

• Biochemical Research: Used as a specific chromogenic or fluorogenic substrate for studying the kinetics and inhibition profiles of various proteases, including chymotrypsin and related serine proteases.
• Pharmaceutical Development: Serves as a key intermediate in the synthesis and screening of novel peptide-based therapeutic agents and enzyme inhibitors.
• Diagnostic Reagent Manufacturing: Employed in the formulation of specialized assay kits for clinical and research laboratories to measure protease activity in biological samples.
• Enzymology Studies: A vital tool for fundamental research into enzyme mechanisms, substrate specificity, and the design of active-site directed probes.
• Quality Control: Acts as a reference standard for the calibration and validation of analytical methods within peptide synthesis and pharmaceutical quality assurance processes.

Basic Information

Product Name	Glutaryl-Gly-Gly-Phe-β-Na
CAS No.	55145-12-5
Molecular Formula	C24H31N5O8Na
Molecular Weight	540.53 g/mol
Synonyms	Glutaryl-Glycyl-Glycyl-L-Phenylalanine β-naphthylamide sodium salt; Nα-Glutaryl-Gly-Gly-Phe-βNA; Glutaryl-Gly-Gly-Phe-2-naphthylamide sodium salt; GGGP-βNA; Protease Substrate GGGP-βNA; L-Phenylalanine, N-[N-[N-[N-(1,5-dioxopentyl)glycyl]glycyl]glycyl]-, 2-naphthalenyl ester, sodium salt; Chymotrypsin Substrate (GGGP-βNA); 55145-12-5
EINECS	Contact for details

Quality Control

Our Glutaryl-Gly-Gly-Phe-β-Na is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are provided to guarantee the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.