Description

4-Hydrazinopyrido[3',2':4,5]thieno[3,2-d]pyrimidine is a high-purity, heterocyclic organic compound featuring a fused pyridothienopyrimidine core with a reactive hydrazine substituent. This specialized structure makes it a critical pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) for targeted cancer therapies and other disease treatments.
• Medicinal Chemistry Research: A versatile scaffold for constructing compound libraries in drug discovery programs, enabling structure-activity relationship (SAR) studies.
• Kinase Inhibitor Development: Core building block for the design and synthesis of potent and selective kinase inhibitors due to its privileged heterocyclic structure.
• Chemical Biology Probes: Used to develop tool compounds for studying biological pathways and target validation in cellular assays.
• Process Chemistry & Scale-Up: Serves as a starting material for optimizing synthetic routes during the transition from laboratory-scale to pilot and commercial-scale production.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-Hydrazinopyrido[3',2':4,5]thieno[3,2-d]pyrimidine
CAS No.	55115-84-9
Molecular Formula	C9H7N5S
Molecular Weight	217.25 g/mol
Synonyms	4-Hydrazinylpyrido[3',2':4,5]thieno[3,2-d]pyrimidine; Pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-ylhydrazine; 4-Hydrazino-9-azathieno[3',2':4,5]pyrido[3,2-d]pyrimidine; Thieno[3,2-d]pyrido[3,2-b]pyrimidin-4-ylhydrazine; CAS 55115-84-9
EINECS	Contact for details

Quality Control

Our 4-Hydrazinopyrido[3',2':4,5]thieno[3,2-d]pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.