Description

3-Amino-5-Bromobenzotrifluoride is a versatile halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino group and a bromine atom on a trifluoromethyl-substituted benzene ring, makes it an indispensable intermediate for constructing complex molecules. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a trifluoromethyl group to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the bromine atom allows for further functionalization via cross-coupling reactions.
• Material Science: Building block for specialty polymers, liquid crystals, and organic electronic materials due to the electron-withdrawing nature of the CF3 group.
• Dye and Pigment Manufacturing: Intermediate for producing high-performance, light-fast dyes and pigments.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to form biaryl and aryl amine structures.
• Research & Development: Valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	3-Amino-5-Bromobenzotrifluoride
CAS No.	54962-75-3
Molecular Formula	C7H5BrF3N
Molecular Weight	240.02 g/mol
Synonyms	5-Bromo-3-(trifluoromethyl)aniline; 3-Amino-5-bromo-alpha,alpha,α-trifluorotoluene; 5-Bromo-3-trifluoromethylaniline; 3-Trifluoromethyl-5-bromoaniline; 1-Amino-3-bromo-5-(trifluoromethyl)benzene; 3-Bromo-5-aminobenzotrifluoride; Benzenamine, 5-bromo-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Bromobenzotrifluoride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, GC for residual solvents, and spectroscopic methods for structural confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment aligns with cGMP principles where applicable, ensuring the material is suitable for demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation. For long-term storage, consider an inert atmosphere to maximize shelf-life stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.