Description

2-(Difluoromethoxy)-5-Nitroaniline is a specialized aromatic amine derivative featuring both nitro and difluoromethoxy functional groups, making it a valuable intermediate in advanced chemical synthesis. This compound is critical for the development of complex molecules where its unique fluorine-containing moiety can impart desirable properties such as metabolic stability and enhanced lipophilicity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoromethoxy group can enhance biological activity.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex azo dyes and high-performance pigments requiring specific light-fastness and color properties.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on fluorinated organic compounds and novel reaction pathways.

Basic Information

Product Name	2-(Difluoromethoxy)-5-Nitroaniline
CAS No.	54939-58-1
Molecular Formula	C7H6F2N2O3
Molecular Weight	204.13 g/mol
Synonyms	5-Nitro-2-(difluoromethoxy)aniline; 2-Amino-4-(difluoromethoxy)nitrobenzene; 2-(Difluoromethoxy)-5-nitrobenzenamine; 1-Amino-2-(difluoromethoxy)-5-nitrobenzene; 54939-58-1; Aniline, 2-(difluoromethoxy)-5-nitro-; 5-Nitro-2-(difluoromethoxy)phenylamine
EINECS	Contact for details

Quality Control

Every batch of 2-(Difluoromethoxy)-5-Nitroaniline is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) documenting batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.