Description

2-Amino-6-Trifluoromethyl-4(1H)-Pyrimidinethione is a high-value heterocyclic building block characterized by its unique pyrimidinethione core and trifluoromethyl substituent. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceuticals and agrochemicals, where it imparts desirable metabolic stability and bioavailability. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of antiviral, anticancer, and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Material Science Precursor: Potential intermediate in the development of specialty polymers or organic electronic materials.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2-Amino-6-Trifluoromethyl-4(1H)-Pyrimidinethione
CAS No.	54845-25-9
Molecular Formula	C5H4F3N3S
Molecular Weight	195.17 g/mol
Synonyms	6-(Trifluoromethyl)-2,4-dihydro-2-imino-4-thioxo-1H-pyrimidine; 2-Amino-4-mercapto-6-(trifluoromethyl)pyrimidine; 2-Amino-6-trifluoromethyl-4-pyrimidinethiol; 4(1H)-Pyrimidinethione, 2-amino-6-(trifluoromethyl)-; 2-Amino-4-thiol-6-trifluoromethylpyrimidine; 6-Trifluoromethyl-2-amino-4-pyrimidinethione; 2-Imino-6-trifluoromethyl-1,4-dihydro-4-thioxopyrimidine
EINECS	Contact for details

Quality Control

Our 2-Amino-6-Trifluoromethyl-4(1H)-Pyrimidinethione is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.