Description

n-Acetyl-D-(Allo)-Isoleucine is a chemically modified, non-proteinogenic amino acid derivative. This compound is valued for its role as a chiral building block and intermediate in advanced organic synthesis, particularly in the pharmaceutical and life sciences sectors. It is essential for researchers and manufacturers developing peptide-based therapeutics, enzyme inhibitors, and other bioactive molecules where stereochemical purity is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel peptide drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis to introduce specific stereochemistry.
• Proteomics & Diagnostics: Potential application in the development of diagnostic reagents and tools for protein analysis.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in the synthesis of complex, enantiomerically pure compounds.

Basic Information

Product Name	n-Acetyl-D-(Allo)-Isoleucine
CAS No.	54831-20-8
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	N-Acetyl-D-alloisoleucine; D-Alloisoleucine, N-acetyl-; (2R,3S)-2-Acetamido-3-methylpentanoic acid; Ac-D-aIle-OH; N-Acetyl-D-α-amino-β-methylvaleric acid; N-Acetyl-(2R,3S)-3-methyl-2-aminopentanoic acid; D-α-Acetamido-β-methylvaleric acid
EINECS	Contact for details

Quality Control

Our n-Acetyl-D-(Allo)-Isoleucine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept sealed under dry, inert conditions to prevent moisture absorption. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% de
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.