Description

2-Methoxy-6-Trifluoromethyl-4-Pyrimidinamine is a high-purity, fluorinated pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in the unique trifluoromethyl and methoxy functional groups, which are instrumental in modulating the biological activity and physicochemical properties of target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Precursor: Employed in the synthesis of specialty chemicals, liquid crystals, and functional materials requiring fluorinated aromatic systems.
• Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke fluorinated compounds for client projects.

Basic Information

Product Name	2-Methoxy-6-Trifluoromethyl-4-Pyrimidinamine
CAS No.	54824-10-1
Molecular Formula	C6H6F3N3O
Molecular Weight	193.13 g/mol
Synonyms	4-Amino-2-methoxy-6-(trifluoromethyl)pyrimidine; 2-Methoxy-6-(trifluoromethyl)pyrimidin-4-amine; 6-Trifluoromethyl-2-methoxypyrimidin-4-ylamine; 4-Pyrimidinamine, 2-methoxy-6-(trifluoromethyl)-; 2-Methoxy-6-trifluoromethylpyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our 2-Methoxy-6-Trifluoromethyl-4-Pyrimidinamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your internal specifications and relevant industry guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids/bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.