Description

Loxapine Hydrochloride is a high-purity pharmaceutical active ingredient, a dibenzoxazepine antipsychotic agent. It is a critical intermediate and active pharmaceutical ingredient (API) for the formulation of antipsychotic medications. This compound is essential for pharmaceutical manufacturers and research institutions developing treatments for schizophrenia and other related psychiatric disorders. Our supply ensures consistent quality and reliable availability for global pharmaceutical production.

Application

• Primary Active Pharmaceutical Ingredient (API) in the manufacture of antipsychotic medications.
• Key intermediate in the synthesis of final dosage forms, such as tablets and capsules.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Raw material for research and development of novel neuropsychiatric therapeutics.
• Used in clinical studies and pharmacological research.
• Essential component for compounding pharmacies requiring specific formulations.

Basic Information

Product Name	Loxapine Hydrochloride
CAS No.	54810-23-0
Molecular Formula	C18H19ClN2O • HCl
Molecular Weight	355.27 g/mol
Synonyms	Loxapine HCl; 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine hydrochloride; Loxapine monohydrochloride; CL-71563; Loxitane (brand name derivative); Sumitomo Loxapine; Oxilapine Hydrochloride; Dibenzo[b,f][1,4]oxazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-, monohydrochloride
EINECS	259-342-5

Quality Control

Our Loxapine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for pharmaceutical use, including identity, purity, and impurity profiles. A Certificate of Analysis (COA) is provided with each shipment, detailing results against relevant pharmacopeial standards (such as USP/EP) and in-house specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.