Description

Somatostatin, Des-Asn(5)- is a synthetic peptide analog of the endogenous hormone somatostatin, specifically lacking the asparagine residue at position 5. This modification can alter its receptor binding profile and metabolic stability, making it a valuable tool for biochemical research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the fields of endocrinology, oncology, and peptide-based drug discovery to study hormone regulation and develop targeted therapeutic agents.

Application

• Biochemical Research: Used as a reference standard and active agent in studies investigating the somatostatin receptor signaling pathways and hormone inhibition mechanisms.
• Pharmaceutical R&D: Serves as a key intermediate or lead compound in the development of novel peptide therapeutics targeting conditions like acromegaly, neuroendocrine tumors, and severe gastrointestinal bleeding.
• Endocrinology Studies: Employed in in vitro and in vivo models to understand the regulation of growth hormone, insulin, and glucagon secretion.
• Diagnostic Agent Development: Potential use in the development of radiolabeled analogs for diagnostic imaging of somatostatin receptor-expressing tumors.
• Cell Biology: Applied in cell culture experiments to study the effects of somatostatin on cell proliferation and apoptosis.

Basic Information

Product Name	Somatostatin, Des-Asn(5)-
CAS No.	54786-81-1
Molecular Formula	C75H104N18O19S2
Molecular Weight	1633.9 g/mol
Synonyms	Des-Asn5-Somatostatin; Somatostatin (1-14), 5-de-L-asparagine-; [Des-Asn5]Somatostatin; Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys; SRIF (1-14), Des-Asn5-; Growth Hormone Release-Inhibiting Factor (1-14), 5-De-L-asparagine-; H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (cyclic 3-14 disulfide)
EINECS	Contact for details

Quality Control

Our Somatostatin, Des-Asn(5)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets high-purity research standards. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvent levels is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Related Peptides (HPLC)	≤ 5.0% total
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC)	≤ 15.0%
Peptide Content (Amino Acid Analysis)	≥ 70.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.