Description

Fortimicin B is a potent aminoglycoside antibiotic belonging to the fortimicin family, known for its broad-spectrum activity against Gram-positive and Gram-negative bacteria. Its significance lies in its role as a key intermediate and reference standard in pharmaceutical research and development, particularly for studying antibiotic mechanisms and resistance. This product is essential for research laboratories, pharmaceutical manufacturers, and quality control units involved in antimicrobial agent development and analytical testing.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified standard for analytical methods, including HPLC, LC-MS, and microbiological assays to ensure product quality and regulatory compliance.
• Antibiotic Research & Development: Serves as a critical intermediate and active component in the R&D of novel antimicrobial agents and combination therapies.
• Microbiological Studies: Employed in in-vitro studies to investigate bacterial susceptibility, minimum inhibitory concentration (MIC), and mechanisms of antibiotic action.
• Quality Control & Assurance: Utilized by QC laboratories in pharmaceutical manufacturing to validate processes and test finished drug products for potency and purity.
• Biochemical Research: Applied in studies exploring protein synthesis inhibition and the interaction of aminoglycosides with bacterial ribosomes.

Basic Information

Item	Detail
Product Name	Fortimicin B
CAS No.	54783-95-8
Molecular Formula	C17H35N5O6
Molecular Weight	405.49 g/mol
Synonyms	Fortimicin B; Antibiotic KA-6606; (2S,3R,4S,5S,6R)-5-Amino-2-[[(2S,3S,4R,5S)-5-[(1S)-1-Aminoethyl]-3,4-dihydroxyoxolan-2-yl]methoxy]-6-(aminomethyl)oxane-3,4-diol; Fortimicin B sulfate; Sperabilin B; Astromicin sulfate intermediate
EINECS	Contact for details

Quality Control

Our Fortimicin B is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and mass spectrometry, to ensure it meets high-grade standards suitable for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and potency. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details
Bacterial Endotoxins	< 1.0 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.