Description

2-(Dimethylamino)Benzotrifluoride is a versatile trifluoromethylated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the electron-donating dimethylamino group and the electron-withdrawing trifluoromethyl group, making it an essential intermediate for constructing complex molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring the trifluoromethyl pharmacophore.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Functional Material Precursor: Employed in the research and development of organic electronic materials, liquid crystals, and dyes.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to form complex biaryl structures.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	2-(Dimethylamino)Benzotrifluoride
CAS No.	54672-14-9
Molecular Formula	C9H10F3N
Molecular Weight	189.18 g/mol
Synonyms	N,N-Dimethyl-2-(trifluoromethyl)aniline; 2-(Trifluoromethyl)-N,N-dimethylaniline; α,α,α-Trifluoro-N,N-dimethyl-o-toluidine; 2-(Dimethylamino)-α,α,α-trifluorotoluene; N,N-Dimethyl-α,α,α-trifluoro-o-toluidine; 2-(N,N-Dimethylamino)benzotrifluoride; o-(Dimethylamino)benzotrifluoride; 2-(Trifluoromethyl)dimethylaniline
EINECS	Contact for details

Quality Control

Our 2-(Dimethylamino)Benzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC, NMR, and Karl Fischer titration, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.