Description

4,6-Dichloro-2-Phenyl-Quinazoline is a versatile and high-value heterocyclic building block with significant importance in advanced organic synthesis. Its core quinazoline scaffold, functionalized with chlorine and phenyl groups, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active quinazoline derivatives.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive scaffold.
• Material Science: Acts as a building block for organic light-emitting diodes (OLEDs) and other electronic materials requiring specific heterocyclic structures.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the quinazoline moiety into more complex molecules.
• Academic & R&D: A valuable compound for medicinal chemistry research and the study of structure-activity relationships (SAR).
• Dye & Pigment Intermediate: Potential use in the synthesis of specialized dyes and pigments.

Basic Information

Product Name	4,6-Dichloro-2-Phenyl-Quinazoline
CAS No.	54665-93-9
Molecular Formula	C14H8Cl2N2
Molecular Weight	275.13 g/mol
Synonyms	2-Phenyl-4,6-dichloroquinazoline; 4,6-Dichloro-2-phenylquinazoline; Quinazoline, 4,6-dichloro-2-phenyl-; 54665-93-9; 2-Phenyl-4,6-dichloro-quinazoline; 4,6-Dichloro-2-phenyl-quinazoline
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-2-Phenyl-Quinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.