Description

5-Amino-4-Chloropyrimidine is a versatile halogenated pyrimidine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its bifunctional reactivity, where the amino and chloro substituents enable selective derivatization to create complex heterocyclic systems. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential building block for the creation of specialized polymers and organic electronic materials.
• Dye & Pigment Manufacturing: Intermediate in the production of certain heterocyclic dyes and colorants.

Basic Information

Product Name	5-Amino-4-Chloropyrimidine
CAS No.	54660-78-5
Molecular Formula	C4H4ClN3
Molecular Weight	129.55 g/mol
Synonyms	4-Chloro-5-aminopyrimidine; 4-Chloro-5-pyrimidinamine; 5-Amino-4-chloro-1,3-diazine; 5-Pyrimidinamine, 4-chloro-; 4-Chloro-1,3-diazin-5-amine
EINECS	Contact for details

Quality Control

Our 5-Amino-4-Chloropyrimidine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.