Description

Cyclo(Di(Threonine)) is a cyclic dipeptide (diketopiperazine) derived from the amino acid threonine. This compound is valued for its role as a versatile chiral building block and scaffold in advanced organic synthesis and pharmaceutical research. It is particularly relevant for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors seeking high-purity intermediates for drug discovery and development.

Application

• As a chiral synthon and building block in the asymmetric synthesis of complex organic molecules and active pharmaceutical ingredients (APIs).
• Utilized in peptidomimetic drug design to create stable, cyclic peptide analogs with potential therapeutic applications.
• Serves as a ligand or catalyst precursor in organometallic chemistry and asymmetric catalysis.
• Used in biochemical research to study enzyme inhibition, protein-protein interactions, and molecular recognition.
• Potential application in the development of cosmeceutical ingredients due to its peptide-based structure.
• As a reference standard in analytical chemistry for method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	Cyclo(Di(Threonine))
CAS No.	54617-73-1
Molecular Formula	C8H14N2O4
Molecular Weight	202.21 g/mol
Synonyms	Cyclo(L-threonyl-L-threonyl); (3S,6S)-3,6-Bis(1-hydroxyethyl)-2,5-piperazinedione; (3S,6S)-3,6-Di(1-hydroxyethyl)-2,5-diketopiperazine; L-Threonine anhydride; Cyclo(L-Thr-L-Thr); Diketopiperazine of L-threonine; 2,5-Piperazinedione, 3,6-bis(1-hydroxyethyl)-, (3S,6S)-; L-Threonine cyclic dipeptide
EINECS	Contact for details

Quality Control

Our Cyclo(Di(Threonine)) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications such as assay, enantiomeric excess, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.