Description

D-Allylglycine is a non-proteinogenic amino acid derivative featuring an allyl side chain, serving as a valuable chiral building block and biochemical tool. Its significance lies in its role as a selective inhibitor of glutamate decarboxylase (GAD), making it a critical compound for neurological and metabolic research. This high-purity intermediate is essential for pharmaceutical R&D, particularly in the synthesis of novel therapeutic agents and as a reference standard in analytical laboratories.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of central nervous system (CNS) active drugs and other bioactive molecules.
• Biochemical Research: Used as a selective inhibitor of glutamate decarboxylase (GAD) to study GABAergic neurotransmission and related neurological pathways.
• Metabolic Studies: Employed in research to investigate amino acid metabolism, enzyme kinetics, and metabolic disorders.
• Peptide Synthesis: Serves as a specialized, non-natural amino acid residue in the design and synthesis of novel peptide-based compounds.
• Analytical Standard: High-purity grade used as a reference standard in HPLC, LC-MS, and other chromatographic methods for quality control and method validation.
• Agrochemical Research: Potential intermediate in the development of advanced crop protection agents and plant growth regulators.

Basic Information

Product Name	D-Allylglycine
CAS No.	54594-06-8
Molecular Formula	C5H9NO2
Molecular Weight	115.13 g/mol
Synonyms	(R)-2-Amino-4-pentenoic acid; D-2-Amino-4-pentenoic acid; (R)-2-Amino-4-pentenoic acid; D-α-Amino-4-pentenoic acid; (R)-α-Amino-4-pentenoic acid; D-4-Pentenoic acid, 2-amino-; (2R)-2-Amino-4-pentenoic acid; Allylglycine, D- isomer
EINECS	Contact for details

Quality Control

Our D-Allylglycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant or inert atmosphere to maintain stability and prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.