Description

Phenol, 4-Butoxy-3-Fluoro- is a fluorinated phenolic ether derivative, characterized by its unique butoxy and fluoro substituents on the aromatic ring. This specific molecular architecture makes it a valuable intermediate for synthesizing advanced materials and fine chemicals where electronic and steric properties are critical. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel compounds with tailored functionalities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom can improve biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for mesogens and electron-transport materials in display technologies, leveraging its ether linkage and fluorine for desired polarity and molecular alignment.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce fluorinated phenyl ether groups into specialty polymers, enhancing chemical resistance and thermal properties.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) as a versatile aryl halide or phenol derivative for constructing complex molecular architectures.

Basic Information

Product Name	Phenol, 4-Butoxy-3-Fluoro-
CAS No.	54509-31-8
Molecular Formula	C₁₀H₁₃FO₂
Molecular Weight	184.21 g/mol
Synonyms	4-Butoxy-3-fluorophenol; 3-Fluoro-4-butoxyphenol; 1-Butoxy-2-fluoro-4-hydroxybenzene; 2-Fluoro-4-hydroxybutoxybenzene; Phenol, 3-fluoro-4-butoxy-; 3-Fluoro-4-n-butoxyphenol; 4-(Butoxy)-3-fluorophenol; FBuOP
EINECS	Contact for details

Quality Control

Every batch of Phenol, 4-Butoxy-3-Fluoro- is produced under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.