Description

7-Methyl-4-Oxo-6,7,8,9-Tetrahydro-4H-Pyrido[1,2-A]Pyrimidine-3-Acetic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex fused-ring structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. It is primarily sought by research organizations, fine chemical manufacturers, and pharmaceutical companies engaged in drug discovery and development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting the central nervous system or other specialized therapeutic areas.
• Organic Synthesis Building Block: Used in research and development for constructing novel heterocyclic compounds due to its reactive ester and ketone functional groups.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies in the search for new bioactive molecules.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value specialty chemicals for various industrial applications.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	7-Methyl-4-Oxo-6,7,8,9-Tetrahydro-4H-Pyrido[1,2-A]Pyrimidine-3-Acetic Acid Ethyl Ester
CAS No.	54504-54-0
Molecular Formula	C₁₃H₁₈N₂O₃
Molecular Weight	250.29 g/mol
Synonyms	Ethyl 7-Methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-3-acetate; 4H-Pyrido[1,2-a]pyrimidine-3-acetic acid, 6,7,8,9-tetrahydro-7-methyl-4-oxo-, ethyl ester; Ethyl 7-methyl-4-oxo-4,6,7,8,9,10-hexahydro-1H-pyrido[1,2-a]pyrimidine-3-carboxylate (tautomeric form); 54504-54-0; Pyrido[1,2-a]pyrimidine derivative
EINECS	Contact for details

Quality Control

Our 7-Methyl-4-Oxo-6,7,8,9-Tetrahydro-4H-Pyrido[1,2-A]Pyrimidine-3-Acetic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, including cGMP-compliant pharmaceutical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed when not in use to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.