Description

6,7,8,9-Tetrahydro-4-Oxo-4H-Pyrido[1,2-A]Pyrimidine-3-Acetic Acid Ethyl Ester is a high-purity, versatile heterocyclic building block and pharmaceutical intermediate of significant commercial importance. This compound is valued for its complex fused pyridopyrimidine structure, which serves as a critical scaffold in medicinal chemistry and advanced organic synthesis. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and cardiovascular pathways.
• Medicinal Chemistry Research: Used as a privileged scaffold for constructing libraries of novel compounds in high-throughput screening and drug discovery programs.
• Agrochemical Synthesis: Serves as a building block for developing advanced pesticides and herbicides with specific modes of action.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, dyes, and functional materials.
• Academic & R&D: Utilized in universities and corporate R&D labs for studying heterocyclic chemistry and reaction mechanisms.
• Contract Manufacturing (CMO/CDMO): Supplied to contract manufacturing organizations for cGMP production of clinical trial materials and commercial APIs.

Basic Information

Product Name	6,7,8,9-Tetrahydro-4-Oxo-4H-Pyrido[1,2-A]Pyrimidine-3-Acetic Acid Ethyl Ester
CAS No.	54504-53-9
Molecular Formula	C13H16N2O3
Molecular Weight	248.28 g/mol
Synonyms	Ethyl 6,7,8,9-tetrahydro-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-acetate; Ethyl 2-(6,7,8,9-tetrahydro-4-oxopyrido[1,2-a]pyrimidin-3-yl)acetate; 4H-Pyrido[1,2-a]pyrimidine-3-acetic acid, 6,7,8,9-tetrahydro-4-oxo-, ethyl ester; Pyrido[1,2-a]pyrimidine derivative; NSC 339586; AABL 01000707; ZINC000003800897; CHEMBL3185142
EINECS	Contact for details

Quality Control

Our production of 6,7,8,9-Tetrahydro-4-Oxo-4H-Pyrido[1,2-A]Pyrimidine-3-Acetic Acid Ethyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements, including those for cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.