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Heparin Magnesium CAS NO 54479-70-8
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CAS No.:54479-70-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Heparin Magnesium is the magnesium salt form of heparin, a naturally occurring glycosaminoglycan anticoagulant. This specific salt form offers distinct stability and handling characteristics, making it a critical intermediate in the production of low molecular weight heparins (LMWHs) and other refined anticoagulant APIs. It is essential for pharmaceutical manufacturers and research institutions focused on cardiovascular therapeutics and blood coagulation research. The compound is identified by CAS No. 54479-70-8.
Application
- Active Pharmaceutical Ingredient (API) Intermediate: Primary use as a key starting material in the synthesis of low molecular weight heparin (LMWH) drugs like enoxaparin, dalteparin, and tinzaparin.
- Anticoagulant Research & Development: Serves as a reference standard and raw material in R&D for novel anticoagulant and antithrombotic agents.
- Biochemical Reagent: Used in laboratory settings for studying heparin-protein interactions, enzyme inhibition assays, and other biochemical studies related to the coagulation cascade.
- Pharmaceutical Excipient: Potential use as an excipient in specific controlled-release or stabilized drug formulations where its polyanionic nature is beneficial.
Basic Information
| Product Name | Heparin Magnesium |
| CAS No. | 54479-70-8 |
| Molecular Formula | (C12H16MgN2O8S2)n (Representative unit) |
| Molecular Weight | Variable (Polymeric Glycosaminoglycan) |
| Synonyms | Heparin Magnesium Salt; Magnesium Heparinate; Heparin Mg; Heparin, magnesium salt; Heparin Magnesium Complex; Magnesium Heparin; Anticoagulant Heparin Magnesium; Heparin Magnesic Salt |
| EINECS | Contact for details |
Quality Control
Our Heparin Magnesium is produced and tested under a strict quality management system. It can be manufactured to meet various pharmacopoeial standards, including USP and EP monographs for Heparin Sodium and its derivatives. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, potency, and impurity profiles, ensuring traceability and compliance for GMP manufacturing.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.
Specification
| Item | Specification |
|---|---|
| Appearance | White or off-white powder |
| Identification (IR) | Conforms to standard |
| Assay (Potency) | ≥ 150 IU/mg (or as per customer requirement) |
| pH (Solution) | 5.0 - 7.5 |
| Loss on Drying | ≤ 5.0 % |
| Residue on Ignition (as MgO) | Contact for details |
| Protein Content | ≤ 0.1 % |
| Heavy Metals | ≤ 20 ppm |
| Bacterial Endotoxins | < 0.03 IU/μg Heparin |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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