Description

1,2,3,4-Tetrahydro-2,4-Dioxo-8-Phenylpyrrolo[1,2-A]-1,3,5-Triazine-7-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific therapeutic pathways. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, where consistent quality and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules and novel APIs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Heterocyclic Compound Synthesis: Serves as a versatile scaffold for constructing fused triazine and pyrrolo-triazine ring systems.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying chemical reactions and developing new synthetic methodologies.

Basic Information

Product Name	1,2,3,4-Tetrahydro-2,4-Dioxo-8-Phenylpyrrolo[1,2-A]-1,3,5-Triazine-7-Carboxylic Acid Ethyl Ester
CAS No.	54449-26-2
Molecular Formula	C₁₆H₁₄N₄O₄
Molecular Weight	326.31 g/mol
Synonyms	Ethyl 1,2,3,4-tetrahydro-2,4-dioxo-8-phenylpyrrolo[1,2-a][1,3,5]triazine-7-carboxylate; 8-Phenyl-1,2,3,4-tetrahydro-2,4-dioxopyrrolo[1,2-a][1,3,5]triazine-7-carboxylic acid ethyl ester; Pyrrolo[1,2-a][1,3,5]triazine-7-carboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-8-phenyl-, ethyl ester; CAS 54449-26-2
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-2,4-Dioxo-8-Phenylpyrrolo[1,2-A]-1,3,5-Triazine-7-Carboxylic Acid Ethyl Ester is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), related substances, and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.