Description

4-Amino-3-Bromobenzotrifluoride is a high-value halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an amino group and a bromine atom on a trifluoromethylated benzene ring, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a trifluoromethyl group to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the bromine atom allows for further functionalization.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart unique chemical resistance, thermal stability, or optical properties.
• Dye & Pigment Manufacturing: Intermediate for producing high-performance, light-fast dyes and pigments.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination, Suzuki coupling) for creating complex biaryl structures.

Basic Information

Product Name	4-Amino-3-Bromobenzotrifluoride
CAS No.	54403-97-3
Molecular Formula	C7H5BrF3N
Molecular Weight	240.02 g/mol
Synonyms	3-Bromo-4-aminobenzotrifluoride; 2-Bromo-α,α,α-trifluoro-p-toluidine; 4-Amino-3-bromo-α,α,α-trifluorotoluene; 3-Bromo-4-(trifluoromethyl)aniline; 4-(Trifluoromethyl)-3-bromoaniline; 2-Bromo-4-amino-benzotrifluoride; p-Amino-m-bromobenzotrifluoride
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Bromobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing identity, purity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	68 - 72 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.