Description

(Z)-3-Amino-2-Methyl-2-Butenoic Acid Ethyl Ester is a high-purity, versatile β-amino acid ester derivative that serves as a critical chiral building block in advanced organic synthesis. Its defined stereochemistry and functional groups make it an essential intermediate for constructing complex molecular architectures with high precision. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of β-lactam antibiotics, protease inhibitors, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides requiring specific stereochemistry.
• Peptidomimetics Research: Serves as a constrained amino acid analog in the design of peptide-like drugs with enhanced metabolic stability.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis and metal complexes.
• Fine Chemical Production: A building block for specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & R&D: Utilized in organic chemistry research for methodological studies and the exploration of new synthetic pathways.

Basic Information

Product Name	(Z)-3-Amino-2-Methyl-2-Butenoic Acid Ethyl Ester
CAS No.	54393-21-4
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	Ethyl (Z)-3-amino-2-methylbut-2-enoate; Ethyl 3-Amino-2-methyl-2-butenoate; (Z)-Ethyl 3-amino-2-methylcrotonate; 2-Butenoic acid, 3-amino-2-methyl-, ethyl ester, (Z)-; 3-Amino-2-methyl-2-butenoic acid ethyl ester; β-Aminocrotonic acid ethyl ester; Ethyl β-aminocrotonate
EINECS	Contact for details

Quality Control

Our (Z)-3-Amino-2-Methyl-2-Butenoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (Z-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.