Description

Poly-(His-Glu)-Poly Ala-Poly Lys CAS NO 54365-32-1 is a synthetic, sequential polypeptide composed of the amino acids histidine, glutamic acid, alanine, and lysine. This engineered structure is significant for its ability to mimic specific protein domains and modulate biological interactions, making it a valuable tool in advanced research and development. It is primarily needed by researchers and manufacturers in the biopharmaceutical and biomedical sectors for applications in drug delivery systems, biomaterial design, and immunological studies.

Application

• Biomaterial and Scaffold Development: Used as a functional component in designing biocompatible scaffolds for tissue engineering and regenerative medicine.
• Drug Delivery Carrier: Serves as a biodegradable and customizable carrier for targeted delivery of therapeutic agents, leveraging its peptide sequence for specific cell targeting.
• Immunological Research: Acts as a model antigen or immunomodulatory agent in vaccine development and immunological assay studies.
• Protein-Mimetic Studies: Utilized in biochemical research to study protein-protein interactions, enzyme activity, and signal transduction pathways.
• Cosmeceutical Formulations: Incorporated into advanced skincare products for its potential bioactive and film-forming properties.
• Bioconjugation and Labeling: Provides a versatile platform for chemical conjugation with drugs, dyes, or other molecules due to its reactive amino acid side chains.

Basic Information

Product Name	Poly-(His-Glu)-Poly Ala-Poly Lys
CAS No.	54365-32-1
Molecular Formula	Contact for details
Molecular Weight	Variable (Sequence-dependent)
Synonyms	Poly(histidine-glutamic acid-alanine-lysine); Poly(His-Glu-Ala-Lys); Sequential Polypeptide (His, Glu, Ala, Lys); HEAK Polymer; Synthetic Tetrapeptide Polymer; Poly(H-E-A-K); (His-Glu-Ala-Lys)n; Poly(L-histidyl-L-glutamyl-L-alanyl-L-lysyl)
EINECS	Contact for details

Quality Control

Our Poly-(His-Glu)-Poly Ala-Poly Lys is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including sequence verification, purity assessment, and impurity profiling, to ensure consistency and performance for research and development purposes. Certificates of Analysis (COA) detailing specific results for purity, amino acid composition, and endotoxin levels are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment away from direct light exposure to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR / NMR)	Conforms to structure
Amino Acid Composition	Conforms to theoretical ratio
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.