Description

5-Pyrimidinecarbonitrile, 4-Amino-2-Chloro-6-(Methylthio) is a high-purity, multi-functional heterocyclic building block of significant commercial importance. This compound serves as a critical synthetic intermediate in the development of advanced active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral, anticancer, and kinase inhibitor drug candidates.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and plant growth regulators.
• Material Science Research: Used in the creation of functionalized organic molecules for advanced materials and ligand synthesis.
• Chemical Biology: Serves as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis: Foundation for contract research organizations (CROs) and CDMOs producing bespoke fine chemicals.

Basic Information

Product Name	5-Pyrimidinecarbonitrile, 4-Amino-2-Chloro-6-(Methylthio)
CAS No.	54356-38-6
Molecular Formula	C6H5ClN4S
Molecular Weight	200.65 g/mol
Synonyms	4-Amino-2-chloro-6-(methylthio)pyrimidine-5-carbonitrile; 2-Chloro-4-amino-6-methylmercaptopyrimidine-5-carbonitrile; 4-Amino-2-chloro-6-methylsulfanylpyrimidine-5-carbonitrile; 2-Chloro-4-amino-6-(methylthio)-5-cyanopyrimidine; 4-Amino-2-chloro-6-(methylsulfanyl)pyrimidine-5-carbonitrile; 4-Amino-2-chloro-6-(methylthio)-5-pyrimidinecarbonitrile
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinecarbonitrile, 4-Amino-2-Chloro-6-(Methylthio) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical and agrochemical synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support compliance with REACH, ISO, and cGMP standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.