Description

4-o-(2-Amino-2-Deoxy-α-D-Glucopyranosyl)-5-o-β-D-Xylofuranosyl-n-[(S)-4-Amino-2-Hydroxybutyryl]-2-Deoxy-D-Streptamine is a structurally complex aminoglycoside derivative, representing a key intermediate or reference standard in advanced pharmaceutical research and development. This compound is of significant interest for its role in the synthesis and study of next-generation antibacterial agents, particularly those designed to overcome microbial resistance. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing novel therapeutics.

Application

• Pharmaceutical Reference Standard: Serves as a high-purity calibrant for analytical methods (HPLC, LC-MS) in quality control and regulatory submissions.
• Antibiotic Research Intermediate: A critical building block in the synthetic pathway for novel semi-synthetic aminoglycoside antibiotics.
• Mechanistic Studies: Used in biochemical and microbiological research to investigate bacterial ribosome targeting and resistance mechanisms.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for complex active pharmaceutical ingredients (APIs).
• Impurity Profiling: Acts as a characterized impurity or degradation product standard for existing aminoglycoside drug substances.

Basic Information

Item	Details
Product Name	4-o-(2-Amino-2-Deoxy-α-D-Glucopyranosyl)-5-o-β-D-Xylofuranosyl-n-[(S)-4-Amino-2-Hydroxybutyryl]-2-Deoxy-D-Streptamine
CAS No.	54333-82-3
Molecular Formula	C23H44N4O15
Molecular Weight	616.61 g/mol
Synonyms	Butirosin B; Ambutyrosin; 4-O-(2-Amino-2-deoxy-α-D-glucopyranosyl)-5-O-β-D-xylofuranosyl-N1-[(S)-4-amino-2-hydroxybutyryl]-2-deoxy-D-streptamine; 2-Deoxy-4-O-(2-deoxy-2-amino-α-D-glucopyranosyl)-5-O-β-D-xylofuranosyl-N3-[(S)-4-amino-2-hydroxybutyryl]-D-streptamine; Antibiotic BB-K 8; Butirosin B sulfate (salt); CAS 54333-82-3
EINECS	Contact for details

Quality Control

Our 4-o-(2-Amino-2-Deoxy-α-D-Glucopyranosyl)-5-o-β-D-Xylofuranosyl-n-[(S)-4-Amino-2-Hydroxybutyryl]-2-Deoxy-D-Streptamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research and development. Comprehensive Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.