Description

Cyclo(-Ala-His) CAS NO 54300-25-3 is a synthetic cyclic dipeptide composed of alanine and histidine residues. This compound is of significant interest in pharmaceutical research and development due to its potential as a building block for more complex peptides and its role in studying biological activity and molecular recognition. It serves as a critical intermediate for researchers and manufacturers in the life sciences sector, particularly those focused on peptide-based therapeutics, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a standard or reference compound in studies of enzyme inhibition, receptor binding, and peptide structure-activity relationships (SAR).
• Cosmetic Peptide Synthesis: Employed in the development of bioactive peptides for advanced skincare and anti-aging formulations.
• Diagnostic Development: Acts as a component in the design of peptide probes and assays for medical diagnostics and biomarker detection.
• Nutraceutical Ingredient: Explored for use in specialized nutraceutical products targeting specific metabolic pathways.
• Academic & Industrial R&D: Provides a versatile scaffold for chemical biology research and the discovery of new bioactive molecules.

Basic Information

Product Name	Cyclo(-Ala-His)
CAS No.	54300-25-3
Molecular Formula	C9H14N4O2
Molecular Weight	210.24 g/mol
Synonyms	Cyclo(Ala-His); Cyclo(L-alanyl-L-histidyl); L-Alanyl-L-histidine cyclic dipeptide; 3-(2-Aminopropyl)-6-(imidazol-4-ylmethyl)piperazine-2,5-dione; Cyclo(alanine-histidine); DKPs (Diketopiperazines) of Ala-His; Cyclo(Ala-His) DKP; Cyclo(L-Ala-L-His)
EINECS	Contact for details

Quality Control

Our Cyclo(-Ala-His) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.