Description

Pyrimidine, 2-(Trichloromethyl)- is a halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the reactive trichloromethyl group attached to the pyrimidine ring, which serves as a versatile precursor for constructing more complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the pyrimidine core is a critical bioactive component.
• Organic Synthesis Building Block: The reactive trichloromethyl group enables various transformations, making it valuable for constructing complex heterocycles and functionalized molecules in R&D.
• Material Science Research: Investigated as a monomer or precursor for the synthesis of specialized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	Pyrimidine, 2-(Trichloromethyl)-
CAS No.	54198-86-6
Molecular Formula	C5H3Cl3N2
Molecular Weight	197.45 g/mol
Synonyms	2-(Trichloromethyl)pyrimidine; 2-Trichloromethylpyrimidine; α,α,α-Trichloro-2-pyrrimidinylmethane; Pyrimidine, 2-(trichloromethyl)-; 2-Pyrimidinyltrichloromethane
EINECS	Contact for details

Quality Control

Our Pyrimidine, 2-(Trichloromethyl)- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.